Research Peptide Comparison
PT-141 and TB-500 are both synthetic peptide compounds of significant research interest, though their structures, receptor interactions, and the biological questions they investigate differ considerably. PT-141 (Bremelanotide) is a cyclic melanocortin agonist that binds MC3R and MC4R with high affinity and has been extensively studied in CNS-focused research. TB-500, derived from Thymosin Beta-4, is a linear peptide involved in actin monomer sequestration, used as a tool compound in tissue remodelling, angiogenesis, and cellular repair studies.
PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin-receptor agonist with primary activity at the MC3R and MC4R subtypes, exerting its effects through central nervous system signalling rather than peripheral vascular pathways. This mechanism has placed it at the centre of research into central arousal circuits, sexual health pharmacology and melanocortin-system pharmacology more broadly.
Compared to TB-500 5mg, PT-141 10mg is priced at £16.99 with 99%+ verified purity. Its CAS registry number is 189691-06-3. It has a molecular weight of 1025.18 g/mol.
PT-141 10mg is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. At £2.00 less than TB-500 5mg, it is the more affordable option in this comparison.
TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring actin-sequestering peptide implicated in cellular migration, cytoskeletal remodelling and tissue regeneration. Research interest focuses on its capacity to upregulate actin polymerisation, modulate inflammatory cytokine profiles and influence anti-fibrotic signalling in cardiac, dermal and musculoskeletal models.
Compared to PT-141 10mg, TB-500 5mg is priced at £18.99 with 99%+ verified purity. Its CAS registry number is 77591-33-4. It has a molecular weight of 4963.50 g/mol.
TB-500 5mg is available in 5mg, 10mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £2.00 higher than PT-141 10mg.
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