Research Peptide Comparison
MOTS-c is a mitochondrial-derived peptide that activates AMPK and modulates metabolic gene expression, while TB-500 is a synthetic Thymosin Beta-4 analogue studied for its role in actin sequestration, cell migration, and angiogenic signalling in tissue repair models. The two peptides represent fundamentally different research paradigms: MOTS-c studies centre on intracellular energy regulation and mitochondrial communication, while TB-500 research focuses on extracellular matrix interactions and motogenic cellular processes.
MOTS-c is a mitochondrially-encoded 16-amino-acid peptide that translocates to the nucleus under metabolic stress and engages the AMPK pathway to coordinate cytoprotective and substrate-utilisation responses. It is a primary subject of mitokine research and of investigations into how mitochondrial-derived signals shape aging, insulin sensitivity, and exercise adaptation.
Compared to TB-500 5mg, MOTS-c 40mg is priced at £65.00 with 99%+ verified purity. Its CAS registry number is 1627580-64-6. It has a molecular weight of 2174.68 g/mol.
MOTS-c 40mg is available in 10mg, 40mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £46.01 higher than TB-500 5mg.
TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring actin-sequestering peptide implicated in cellular migration, cytoskeletal remodelling and tissue regeneration. Research interest focuses on its capacity to upregulate actin polymerisation, modulate inflammatory cytokine profiles and influence anti-fibrotic signalling in cardiac, dermal and musculoskeletal models.
Compared to MOTS-c 40mg, TB-500 5mg is priced at £18.99 with 99%+ verified purity. Its CAS registry number is 77591-33-4. It has a molecular weight of 4963.50 g/mol.
TB-500 5mg is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. At £46.01 less than MOTS-c 40mg, it is the more affordable option in this comparison.
All products sold by Neovia Peptides are strictly for in-vitro research and laboratory use only. Not intended for human or veterinary use, food additives, drugs, or cosmetics. By purchasing from this website, you agree that you understand and accept these terms.
