Research Peptide Comparison
Human Chorionic Gonadotropin (HCG) is a heterodimeric glycoprotein hormone that acts as a structural and functional analogue of luteinising hormone (LH), binding the LH/hCG receptor on Leydig cells and gonadal tissue to stimulate steroidogenic pathways. MOTS-c is a 16-amino acid peptide of mitochondrial genomic origin whose primary research interest lies in its capacity to activate AMPK, modulate folate and methionine metabolism, and act as a retrograde mitochondrial signal influencing nuclear transcription under conditions of metabolic stress. The comparison of an LH-mimetic glycoprotein operating through a classical GPCR-cAMP signalling cascade with a mitochondrially derived metabolic peptide reflects the breadth of mechanistic diversity researchers explore when investigating systemic hormonal and cellular energy networks.
Human Chorionic Gonadotropin (hCG) is a placental glycoprotein hormone that binds the luteinising hormone (LH) receptor, driving downstream steroidogenic signalling in gonadal tissue. Its near-identical receptor affinity to endogenous LH makes it a standard probe in hypothalamic-pituitary-gonadal (HPG) axis investigation, reproductive endocrinology, and Leydig and theca cell stimulation studies.
Compared to MOTS-c 40mg, HCG 5000iu is priced at £23.99 with 99%+ verified purity. Its CAS registry number is 9002-61-3. It has a molecular weight of 36.7 kDa.
HCG 5000iu is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. At £41.01 less than MOTS-c 40mg, it is the more affordable option in this comparison.
MOTS-c is a mitochondrially-encoded 16-amino-acid peptide that translocates to the nucleus under metabolic stress and engages the AMPK pathway to coordinate cytoprotective and substrate-utilisation responses. It is a primary subject of mitokine research and of investigations into how mitochondrial-derived signals shape aging, insulin sensitivity, and exercise adaptation.
Compared to HCG 5000iu, MOTS-c 40mg is priced at £65.00 with 99%+ verified purity. Its CAS registry number is 1627580-64-6. It has a molecular weight of 2174.68 g/mol.
MOTS-c 40mg is available in 10mg, 40mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £41.01 higher than HCG 5000iu.
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