Research Peptide Comparison
KPV Alpha and TB-500 are both research peptides with proposed roles in modulating inflammatory and repair-related processes, yet they operate through distinct molecular mechanisms. KPV Alpha is a tripeptide fragment of α-MSH investigated for its capacity to interact with melanocortin receptors on immune and epithelial cells, with preclinical studies examining its effects on pro-inflammatory cytokine signalling. TB-500, a synthetic Thymosin Beta-4 analogue, functions primarily through actin sequestration and modulation of actin-G/F equilibrium, influencing cellular migration, angiogenesis, and extracellular matrix remodelling.
KPV is the C-terminal Lysine-Proline-Valine tripeptide of α-melanocyte-stimulating hormone (α-MSH) and retains a substantial portion of the parent peptide's anti-inflammatory activity in a markedly smaller scaffold. It modulates NF-κB signalling and downstream pro-inflammatory cytokine output, making it a frequent probe in mucosal inflammation, epithelial barrier and immune-cell research.
Compared to TB-500 5mg, KPV Alpha 10mg is priced at £29.99 with 99%+ verified purity. Its CAS registry number is 67727-97-3. It has a molecular weight of 357.45 g/mol.
KPV Alpha 10mg is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £11.00 higher than TB-500 5mg.
TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring actin-sequestering peptide implicated in cellular migration, cytoskeletal remodelling and tissue regeneration. Research interest focuses on its capacity to upregulate actin polymerisation, modulate inflammatory cytokine profiles and influence anti-fibrotic signalling in cardiac, dermal and musculoskeletal models.
Compared to KPV Alpha 10mg, TB-500 5mg is priced at £18.99 with 99%+ verified purity. Its CAS registry number is 77591-33-4. It has a molecular weight of 4963.50 g/mol.
TB-500 5mg is available in 5mg, 10mg and ships with a full Certificate of Analysis from Janoshik Analytical. At £11.00 less than KPV Alpha 10mg, it is the more affordable option in this comparison.
All products sold by Neovia Peptides are strictly for in-vitro research and laboratory use only. Not intended for human or veterinary use, food additives, drugs, or cosmetics. By purchasing from this website, you agree that you understand and accept these terms.
