Research Peptide Comparison
KPV Alpha is a C-terminal tripeptide derivative of α-melanocyte-stimulating hormone (α-MSH) that retains the core anti-inflammatory signalling activity of its parent molecule, with preclinical research focusing on its interaction with melanocortin receptors and downstream modulation of NF-κB-mediated inflammatory pathways in cellular models. MOTS-c is a mitochondrially encoded peptide regulator of AMPK and metabolic gene expression, with research interest centred on its role in systemic metabolic homeostasis, mitochondrial stress responses, and longevity-associated signalling pathways. The pairing of an anti-inflammatory melanocortin fragment with a mitochondrial metabolic peptide represents a research intersection of innate immune regulation and organelle-level energy sensing.
KPV is the C-terminal Lysine-Proline-Valine tripeptide of α-melanocyte-stimulating hormone (α-MSH) and retains a substantial portion of the parent peptide's anti-inflammatory activity in a markedly smaller scaffold. It modulates NF-κB signalling and downstream pro-inflammatory cytokine output, making it a frequent probe in mucosal inflammation, epithelial barrier and immune-cell research.
Compared to MOTS-c 40mg, KPV Alpha 10mg is priced at £29.99 with 99%+ verified purity. Its CAS registry number is 67727-97-3. It has a molecular weight of 357.45 g/mol.
KPV Alpha 10mg is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. At £35.01 less than MOTS-c 40mg, it is the more affordable option in this comparison.
MOTS-c is a mitochondrially-encoded 16-amino-acid peptide that translocates to the nucleus under metabolic stress and engages the AMPK pathway to coordinate cytoprotective and substrate-utilisation responses. It is a primary subject of mitokine research and of investigations into how mitochondrial-derived signals shape aging, insulin sensitivity, and exercise adaptation.
Compared to KPV Alpha 10mg, MOTS-c 40mg is priced at £65.00 with 99%+ verified purity. Its CAS registry number is 1627580-64-6. It has a molecular weight of 2174.68 g/mol.
MOTS-c 40mg is available in 10mg, 40mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £35.01 higher than KPV Alpha 10mg.
All products sold by Neovia Peptides are strictly for in-vitro research and laboratory use only. Not intended for human or veterinary use, food additives, drugs, or cosmetics. By purchasing from this website, you agree that you understand and accept these terms.
