Research Peptide Comparison
Kisspeptin and PT-141 (Bremelanotide) both occupy a fascinating intersection of neuroendocrine and reproductive research, each influencing aspects of reproductive physiology through distinct receptor mechanisms. Kisspeptin signals through the GPR54/KISS1R receptor to activate hypothalamic GnRH neurons, functioning as a critical upstream regulator of the HPG axis. PT-141 is a cyclic heptapeptide analogue of α-MSH acting as a melanocortin receptor agonist — primarily at MC3R and MC4R — engaging central nervous system pathways rather than directly modulating gonadotropin release.
Kisspeptin-10, the C-terminal decapeptide fragment of metastin, is the minimal active sequence at the KISS1R (GPR54) receptor and a primary upstream regulator of GnRH neuron firing. By controlling pulsatile GnRH release, it sits at the apex of the hypothalamic-pituitary-gonadal (HPG) axis and has become a central tool in fertility, puberty-onset and reproductive endocrinology investigation.
Compared to PT-141 10mg, Kisspeptin 5mg is priced at £18.99 with 99%+ verified purity. Its CAS registry number is 374675-21-5. It has a molecular weight of 1302.48 g/mol.
Kisspeptin 5mg is available in 5mg, 10mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £2.00 higher than PT-141 10mg.
PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin-receptor agonist with primary activity at the MC3R and MC4R subtypes, exerting its effects through central nervous system signalling rather than peripheral vascular pathways. This mechanism has placed it at the centre of research into central arousal circuits, sexual health pharmacology and melanocortin-system pharmacology more broadly.
Compared to Kisspeptin 5mg, PT-141 10mg is priced at £16.99 with 99%+ verified purity. Its CAS registry number is 189691-06-3. It has a molecular weight of 1025.18 g/mol.
PT-141 10mg is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. At £2.00 less than Kisspeptin 5mg, it is the more affordable option in this comparison.
All products sold by Neovia Peptides are strictly for in-vitro research and laboratory use only. Not intended for human or veterinary use, food additives, drugs, or cosmetics. By purchasing from this website, you agree that you understand and accept these terms.
