Research Peptide Comparison
Human Chorionic Gonadotropin (HCG) and Tesamorelin are both peptide-based research tools with endocrine activity, yet they act on entirely separate hormonal axes. HCG is a heterodimeric glycoprotein that binds luteinising hormone receptors (LH-R) in gonadal tissue, and its biochemical characterisation has been extensively documented in the reproductive endocrinology literature. Tesamorelin engages pituitary GHRH receptors to drive somatotroph GH secretion, operating within the hypothalamic–pituitary–somatotropic axis with no direct interaction with gonadotropin signalling.
Human Chorionic Gonadotropin (hCG) is a placental glycoprotein hormone that binds the luteinising hormone (LH) receptor, driving downstream steroidogenic signalling in gonadal tissue. Its near-identical receptor affinity to endogenous LH makes it a standard probe in hypothalamic-pituitary-gonadal (HPG) axis investigation, reproductive endocrinology, and Leydig and theca cell stimulation studies.
Compared to Tesamorelin 5mg, HCG 5000iu is priced at £23.99 with 99%+ verified purity. Its CAS registry number is 9002-61-3. It has a molecular weight of 36.7 kDa.
HCG 5000iu is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. At £16.00 less than Tesamorelin 5mg, it is the more affordable option in this comparison.
Tesamorelin is a synthetic analog of human growth hormone-releasing hormone (GHRH) modified at the N-terminus to confer resistance to enzymatic degradation and prolong receptor engagement. It is one of the more thoroughly characterised GHRH analogs in metabolic research, with literature focused on visceral adipose tissue reduction, IGF-1 dynamics and lipid-profile modulation.
Compared to HCG 5000iu, Tesamorelin 5mg is priced at £39.99 with 99%+ verified purity. Its CAS registry number is 218949-48-5. It has a molecular weight of 5135.90 g/mol.
Tesamorelin 5mg is available in 5mg, 10mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £16.00 higher than HCG 5000iu.
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