Research Peptide Comparison
Human Chorionic Gonadotropin (HCG) and Ipamorelin are both used extensively in preclinical research contexts, yet they act on fundamentally different endocrine axes and bear no mechanistic overlap. HCG is a glycoprotein hormone and potent LH-receptor agonist, widely employed in reproductive biology, steroidogenesis research, and HPG axis studies. Ipamorelin is a short-chain pentapeptide that selectively engages the ghrelin receptor (GHS-R1a) to elicit pulsatile growth hormone secretion, operating entirely within the somatotropic rather than gonadotropic axis.
Human Chorionic Gonadotropin (hCG) is a placental glycoprotein hormone that binds the luteinising hormone (LH) receptor, driving downstream steroidogenic signalling in gonadal tissue. Its near-identical receptor affinity to endogenous LH makes it a standard probe in hypothalamic-pituitary-gonadal (HPG) axis investigation, reproductive endocrinology, and Leydig and theca cell stimulation studies.
Compared to Ipamorelin 5mg, HCG 5000iu is priced at £23.99 with 99%+ verified purity. Its CAS registry number is 9002-61-3. It has a molecular weight of 36.7 kDa.
HCG 5000iu is available in single size and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £4.00 higher than Ipamorelin 5mg.
Ipamorelin is a pentapeptide growth hormone-releasing peptide (GHRP) and selective agonist of the ghrelin (GHS-R1a) receptor. It is widely cited for its capacity to stimulate pituitary GH release without the cortisol, prolactin or aldosterone elevations associated with earlier GHRPs, making it a clean reference ligand in somatotropic and receptor-selectivity research.
Compared to HCG 5000iu, Ipamorelin 5mg is priced at £19.99 with 99%+ verified purity. Its CAS registry number is 170851-70-4. It has a molecular weight of 711.85 g/mol.
Ipamorelin 5mg is available in 5mg, 10mg and ships with a full Certificate of Analysis from Janoshik Analytical. At £4.00 less than HCG 5000iu, it is the more affordable option in this comparison.
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