Research Peptide Comparison
GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) found in human plasma, widely studied for its capacity to upregulate collagen and glycosaminoglycan synthesis, modulate matrix metalloproteinase activity, and activate wound-repair gene networks. SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that localises to cardiolipin at the inner mitochondrial membrane, reducing oxidative stress and preserving electron transport chain efficiency in models of cellular ageing and ischaemic injury. Mechanistically, GHK-Cu operates through extracellular matrix remodelling and transcriptional programmes associated with tissue regeneration, whereas SS-31 intervenes at the level of organelle bioenergetics and redox homeostasis. Researchers working in anti-ageing or tissue biology may compare these peptides to explore how extracellular repair signals and intracellular mitochondrial protection interact within the same experimental model.
GHK-Cu is a copper-binding tripeptide (glycyl-L-histidyl-L-lysine:Cu²⁺) present endogenously in human plasma, saliva and urine, with circulating concentrations diminishing measurably with age. The literature characterises its influence on extracellular matrix remodelling, fibroblast activation and broad transcriptomic modulation across genes linked to repair, antioxidant defence and angiogenesis.
Compared to SS-31 10mg, GHK-Cu 100mg is priced at £34.99 with 99%+ verified purity. Its CAS registry number is 49557-75-7. It has a molecular weight of 403.93 g/mol.
GHK-Cu 100mg is available in 50mg, 100mg and ships with a full Certificate of Analysis from Janoshik Analytical. It is priced £5.00 higher than SS-31 10mg.
SS-31 (Elamipretide) is a synthetic aromatic-cationic tetrapeptide that selectively concentrates in the inner mitochondrial membrane and binds cardiolipin, stabilising cristae architecture and supporting electron-transport chain efficiency. It is a leading mitochondria-targeted research compound in models of ischaemia-reperfusion injury, heart failure, and age-related mitochondrial decline.
Compared to GHK-Cu 100mg, SS-31 10mg is priced at £29.99 with 99%+ verified purity. Its CAS registry number is 736992-21-5. It has a molecular weight of 640.75 g/mol.
SS-31 10mg is available in 10mg, 50mg and ships with a full Certificate of Analysis from Janoshik Analytical. At £5.00 less than GHK-Cu 100mg, it is the more affordable option in this comparison.
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